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Molecular
analysis of type III polyketide synthase (PKS) gene family
from Zingiber officinale Rosc
Radhakrishnan E. K. and E. V. Soniya*
Plant Molecular Biology Division, Rajiv Gandhi Centre
for Biotechnology, Thiruvananthapuram,
Kerala, India-695 014.
*Corresponding author. E-mail:
evsoniya@rgcb.res.in.
Tel.: 91-471-2529454. Fax: 91-471-2348096.
Accepted 20 March, 2009
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Enzymes of the type III polyketide synthase family is
considered to have significant role in biosynthesis of
structurally diverse polyketide scaffolds in Zingiber
officinale. Genome wide analysis of polyketide synthase
gene family in Z. officinale identified partial
sequences of six members. Comparative sequence analysis
showed that four of them ZoPKS2, 3, 4 and 6 were novel forms
as revealed by the significant variations at the highly
conserved regions. Phylogenetic analysis also showed
separate clustering of the novel forms along with the
non-chalcone forming PKSs. This sequence identified in the
study forms the first and basic information of the PKS gene
family from the Zingiberaceae.
Key words:
Zingiber officinale,
CHS, PKS, multigene family, phylogenetic analysis.. |