Saeed and Omer. Synthesis of some 2,5- diamino-3,6- dibromo -1,4-benzoquinones. Afr.J. Pure Appl.Chem. 2009

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Full Length Research Paper

Synthesis of some 2,5- diamino-3,6- dibromo -1,4-benzoquinones

A. E. M. Saeed¹*and N. M. A. Omer²

¹Chemistry Department, College of Science, Sudan University of Science and Technology, P. O. Box 407 Khartoum , Sudan.

²Chemistry Department, Faculty of Science, University of Khartoum, P. O. Box 1996, Khartoum, Sudan.

*Corresponding author. E-mail: ahmedelsadig@yahoo.com

Accepted 23 November, 2009.

Abstract

A group of 19 compounds of the type 2,5-diamino-3,6-dibromo-1,4-benzoquinones were prepared and spectroscopically elucidated through IR ,UV-VIS, NMR and MS. Coupling of the intermediate 2,3,5,6-tetra bromo-benzoquinone with the required aryl amines furnished the required compounds. The prepared compounds were found to possess antimicrobial activities when tested against four standard bacterial organisms and two standard fungal organisms.

Key words: p-quinones, synthesis, antimicrobial.

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