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Oxovanadium (IV) esters of
ciprofloxacin: Their characterization and potentiometric
study
Saira Shahzadi1*
and Saqib Ali2*
1Department
of Chemistry, GC University,
Faisalabad,
Pakistan.
2Department
of Chemistry, Quaid-i-Azam University, 45320 Islamabad,
Pakistan.
*Corresponding author. E-mail:
drsa54@yahoo.com;
sairashahzadi@yahoo.com
Accepted
23 June, 2008 |
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The reaction between
ciprofloxacin and VOSO4.3H2O in 1:1, 1:2 and 1:3
molar ratio in methanol was investigated at 20˚C, 0˚C and -10˚C. In
various pH conditions the different complexes which are formulated as
VO(H2O)3L, VO(H2O)L2 and VL3
have been formed by titration of VOSO4.3H2O
with ciprofloxacin in the presence of NaOH. These complexes have been
characterized by IR spectroscopy. The order
of stability is estimated as 1:1 >1:3 >1:2 which is justified by the
proposed mechanism.
Key words: Oxovanadium(IV) esters, IR, potentiometric study, stability constant. |
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