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Antidermatophytic
activities of Ixora brachiata Roxb
B. Sadeghi-Nejad1* and S. S Deokule2
1Department
of Mycoparasitology, Medical school, Joundi-Shapour
University of Medical Sciences, Ahwaz, Iran.
2Department
of Botany, University of Pune Ganeshkhind, Pune- 411007,
India.
*Corresponding author. E-mail:
batsad4@yahoo.com .
Accepted
5 August, 2009 |
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The
in vitro antifungal activity of Ixora brachiata Roxb.
leaf and root extracts were evaluated against three
different genera of dermatophytes viz. Microsporum,
Trichophyton and Epidermophyton by Dilution
Agar Method. The crude extracts of Ixora brachiata
root and leaf showed in-vitro antifungal properties
and completely prevented the growth of tested dermatophytic
species with minimum inhibitory concentration (MIC) values
of I. brachiata leaf (IBL) and I. brachiata
root (IBR) between 5.0 - 10 and 2.5 - 10 mg ml-1
medium, respectively. Minimum fungicidal concentration (MFC)
values of I. brachiata leaf (IBL) and I. brachiata
root (IBR) was also similar to 5.0 and 2.5 mg ml-1
of the medium, respectively. Results of phytochemical
screening indicated that the leaf and root of I.
brachiata gave positive test for starch, saponins,
reducing sugars, anthraquinones, glycosides, phenols and
proteins while they gave negative test for alkaloids. IBL
gave positive test for tannins while IBR gave positive test
for flavonoids. Detection of coumarins and triterpenes in
IBL suggested that these compounds might be responsible for
the anti-dermatophytic activity in this study.
Key
words:
Antidermatophytic activity, Ixora brachiata Roxb. |
