African Journal of Biotechnology Vol. 2 (12), pp.662-671, December 2003

ISSN 1684-5315  © 2003 Academic Journals

Review

African indigenous plants with chemotherapeutic potentials and biotechnological approach to the production of bioactive prophylactic agents

E. Olatunde Farombi

Drug Metabolism and Toxicology Unit, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan Nigeria. E-mail: olatunde_farombi@yahoo.com or ofarombi@skannet.com. Fax: 234-2-8103043 or 8103118.

Accepted  25 November 2003

Undoubtedly medicinal plants are relevant in both developing and developed nations of the world as sources of drugs or herbal extracts for various chemotherapeutic purposes. Also the use of plant-derived natural compounds as part of herbal preparations as alternative sources of medicaments continues to play major roles in the general wellness of people all over the world. The African continent contains some of the richest biodiversity in the world, and abounds in plants of economic importance and plants of medicinal importance which when developed would reduce our expenditure on imported drugs to meet our health needs. Herbal-based and plant-derived products can be exploited with sustainable comparative and competitive advantage. This review presents some indigenous African plants with chemotherapeutic properties and possible ways of developing them into potent pharmacological agents using biotechnological approaches.

Key words: Antioxidants, chemotherapy, medicinal plants, biotechnology, tissue culture, phytochemicals, prophylaxis, african plants, herbs, natural products.