crude polysaccharides from Purslane on fatigue
induced by forced swimming
Chen Xiang1, Zheng Xiaowei2,
Lou Xiaojuan3*, Huang Yong4, Zhang
Guohai1, Guo Xueqi3, Qian Jin3,
Pan Yuexian3 and Yang Yongping3
College, Wenzhou University, Wenzhou 325035, PR China.
2Department of Physical
Education and Military Training, Zhejiang University of
Technology, Hangzhou, 310014 PR China.
College, Donghua University, Shanghai 201620, PR China.
College, Tongji University, Shanghai 200092, PR China.
*Corresponding author. E-mail:
Polysaccharides from Purslane;
low-dose PFP supplemented group;
middle-dose PFP supplemented group;
high-dose PFP supplemented group;
blood lactic acid;
serum urea nitrogen.
Accepted 28 December, 2011
The objective of this study was to investigate the effects
of crude polysaccharides from Purslane (PFP)
supplementation on fatigue induced by forced swimming in
mice. 96 mice were divided randomly into four groups:
Control group (CG), low-dose PFP supplemented group (PFP-LG),
middle-dose PFP supplemented group (PFP-MG) and high-dose
PFP supplemented group (PFP-HG). Each group contains 24
animals. All were administered orally and daily for 4 weeks.
Control group received isotonic saline solution (50 ml/kg
bodyweight); and supplemented groups orally obtained 100,
200 and 400 mg/kg bodyweight of PFP in appropriate volumes
of physiological saline. Changes of the body weights of the
mice were observed during initial and terminal stages of the
experiment along with the swimming capacity and
corresponding biochemical parameters including blood lactic
acid (BLA), serum urea nitrogen (SUN) and hepatic glycogen.
The results of this study showed that PFP supplementation
could extend the swimming time to exhaustion of the mice, as
well as increase the hepatic glycogen contents, while
decreasing the BLA and SUN contents. These indicated that
PFP could alleviate fatigue induced by forced swimming in
Crude polysaccharides from Purslane, fatigue, forced