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Study on serum
fluorescence spectra based on wavelet transform
Zhu Weihua1,2,
Zhao Zhimin1*, Guo Xin1 and Hong
Xiaoqin1
1College
of Science, Nanjing University of Aeronautics and
Astronautics, Nanjing, 210016, China.
2College
of Science, Hohai University, Nanjing, 210098, China.
*Corresponding author. E-mail:
zhaozhimin@nuaa.edu.cn.
Accepted 24 November, 2009 |
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Blood plays an important role in clinical diagnosis and
treatment and as such, the analysis of blood spectrum will
be of very important practical significance. Serum
fluorescence emission intensity is closely related with the
excitation wavelength; when the excitation wavelength is 230
nm, the blood lipid concentration and fluorescence intensity
was significantly correlated. On the contrary, blood sugar
was almost with no effect on the strength. Wavelet analysis
was used in signal de-noising to get a wide range of
applications. In this paper, fluorescence spectrum was
divided into four layers by db4 wavelet, according to the
principle of stein unbiased likelihood estimate.To choose
the threshold, noise was removed and reconstruction signal
received. This paper studied the correlation between blood
lipid concentration and original fluorescence intensity,
reconstruction fluorescence intensity and the fourth layer
fluorescence strength. Some significant results were
achieved, providing an experimental basis for further study
on the fluorescence spectrum of blood.
Key words:
Serum fluorescence spectrum, wavelet transform, blood lipid. |
