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Effect of Ramadan fasting
on glucose,
glycosylated haemoglobin, insulin,
lipids and
proteinous
concentrations in
women with non-insulin dependent diabetes mellitus
Ait saada, D.1*, Selselet
attou, G.1, Belkacemi, L.1, Ait
chabane, O.1, Italhi, M.2, Bekada, A.
M. A.3 and Kati, D.4
1Department
of Biology, Faculty of Sciences, University of Abdel Hamid
Ibn Badis, 27000 Mostaganem, Algeria.
2Hospital
of Aine Tedles Mostaganem, Algeria.
3Department
of Biology, University Essania, Oran, Algeria.
4University
of Montpelier, France.
*Corresponding author. E-mail:
aitsaadad@yahoo.fr.
Accepted 13
November, 2009 |
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The objective of this study was to investigate the effect of
Ramadan fasting on body mass index (BMI)
and on certain biochemical parameters of serum
in women patients with non-insulin dependent diabetes
mellitus. Sixty-six subjects from 3 regions located in the
west of Algeria participated in this study. All
participating patients were studied a week before Ramadan
and at the third week of Ramadan fasting. No statistically
significant fluctuations were noted in BMI either during
Ramadan or in non-fasting days.
However, the rates of glycosylated haemoglobin (HbA1c)
decreased slightly (P < 0.05) during the last week of the
month of Ramadan among the diabetic patients. Also, the glucose levels were
significantly
(p < 0.05)
higher in the serum subjects of patients during the fasting
period when compared to the level before Ramadan.
This could be due to the significant decrease (P < 0.05) of
insulin levels in patients during the fasting period.
The rates of HDL
cholesterol
recorded
in the
blood
among patients rose
significantly (p < 0.05)
during the Ramadan
than
during the non-fasting period.
The
statistically significant increase in HDL-cholesterol
explains clearly the beneficial effect of Ramadan fasting on
diabetic’s serum lipids.
Moreover,
serum total cholesterol, triglyceride, LDL cholesterol and
VLDL cholesterol levels decreased significantly (p <
0.05) during the third week of Ramadan than non-fasting day.
As for proteinous compounds (protein, creatin and urea),
their plasmatic rates all increased substantially (p < 0.05)
in patients during the fasting period of the month of
Ramadan.
Key
words:
Fasting, ramadan,
type 2
diabetes. |
