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Antibacterial activity and phytochemical analysis of leaf
extracts of Lasienthera africanum
Adegoke, Anthony A.1 and Adebayo-tayo, Bukola C.2
1Department
of Microbiology, University of Uyo, Uyo, Akwa Ibom State,
Nigeria.
2Department
of Botany and Microbiology, University of Ibadan, Ibadan,
Oyo State, Nigeria.
*Corresponding author.
E-mail: anthonyadegoke@yahoo.co.uk. Tel: 2348038398510
Accepted 19 November, 2008 |
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The phytochemical analysis
of both the aqueous and methanolic extracts of edible
indigenous medicinal plant Lasienthera africanum
(“Editan”) and their antibacterial activities against
clinical isolates, Escherichia coli, Salmonella typhi,
Klebsiella pneumoniae and Staphylococcus aureus
were investigated. The phytochemical analysis revealed the
presence of alkaloids, saponins, tannins, flavonoids,
cardiac glycosides, anthraquinones and cyanogenetic gly-cosides
in varying concentration. Both the methanolic and aqueous
extracts inhibited the growth of the test organisms with
Sal. typhi showing the highest susceptibility. This
research supports the local use of the leaf of the plant,
L. africanum (“Editan”) for prophylactic and
therapeutic purposes against bacterial infection.
Key words:
Lasienthera africanum, phytochemical analysis,
antimicrobial activity, activity index, therapeutic purpose. |
