Full Length Research Paper

Effect of Cassia hirsuta (L) extract on DNA profile of some microorganisms

M. K. Oladunmoye, F. C. Adetuyi and F. A. Akinyosoye

Department of Microbiology, Federal University of Technology, Akure, Nigeria.

*Corresponding author E-mail: chourlar@yahoo.com.

Accepted 11 August, 2006

The effect of ethanol extract of leaf of Cassia hirsute (L) on the DNA profile of some selected pathogenic microorganisms were investigated using PCR-RAPD analysis to generate DNA fingerprint. The change in molecular configuration of organisms with and without extract shows a wide disparity between the sensitive and the resistant organism. Thus, this study demonstrates that some of the organisms are susceptible to the antimicrobial activity of C. hirsute extract while others are resistant.

Key words: Cassia hirsuta, DNA finger printing, antimicrobial activity.