Full Length Research Paper

Enzymatic hydrolysis of esters from 2-carboxy-6-methoxy-2,3-dihydrobenzofuran acid

Ricardo Tovar-Miranda¹*, Raúl Cortés-García¹, Samuel Cruz-Sánchez¹, Rodolfo Méndez Bellido¹, Arturo Coaviche¹ and Héctor Luna²

¹Instituto de Ciencias Básicas, Universidad Veracruzana, Av. Dr. Rafael Sánchez Altamirano s/n Col. Industrial Animas, C.P. 91190 Xalapa, Ver. México.

²Departamento de Sistemas Biológicos. Universidad Autónoma Metropolitana-Xochimilco. Calz. del Hueso No. 1100, Col. Villa Quietud, Coyoacán, México, D.F. 04960 México.

*Corresponding author. E-mail: rtovar@uv.mx Tel. +1 228 841-89-00. Ext. 13168. Fax: +1 228 841-89-32.

Accepted 21 September, 2009

   Abstract

In this work we describe the results of the enzymatic hydrolysis of esters from 2-carboxy-6-methoxy-2,3-dihydrobenzofuran acid using Candida antarctica lipase supported on acrylic resin, with enantiomeric excesses ranging between 80 to 99%.

Key words: 2-Carboxy-6-methoxy-2,3-dihydrobenzofuran acid, Candida antarctica lipase, enantioselective hydrolysis.