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In vitro
activity of certain drugs in combination with plant extracts
against Staphylococcus aureus infections
Ghaleb Mohamma Adwan1*, Bassam
Ali Abu-shanab2 and Kamel Mohammad Adwan1
1Department
of Biology and Biotechnology, An-Najah N. University, Nablus,
Palestine.
2Faculty
of Veterinary Medicine, An-Najah N. University, Nablus,
Palestine.
*Corresponding author. E-mail:
adwang@najah.edu
Fax: +972-9-2347488.
Accepted 23 October, 2007 |
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This study has been done to evaluate the interaction
between ethanolic extracts of Rhus coriaria (leaf),
Psidium guajava (Leaf), Lawsonia inermis (Leaf),
and Sacropoterium spinosum (seed) and antimicrobial
drugs including oxytetracyclin HCl, enrofloxacin, gentamicin
sulphate, and sulphadimethoxin against 4 clinical isolates
of methicillin-resistant Staphylococcus aureus (MRSA).
This evaluation was done by well-diffusion method. Results
of this study showed that crude extracts from these plants
increase the inhibition zones of oxytetracyclin HCl,
gentamicin sulphate, and sulphadimethoxin, while combination
between the plant extracts and enrofloxacin decreases
inhibition zone.
Key words:
Plant extract, antibiotics, drugs, synergism, antagonism,
Staphylococcus aureus. |
