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Effects of
polysaccharide from Lycium barbarum
in alloxan-induced
diabetic mice
Zhengwei
Zhou1, Longjun Jing2*, Guowen Cui3,
Qiang Feng2 and Yuanshi Xiao2
1Hunan
City University, Yiyang, Hunan Province, 413000, P. R.
China.
2Qujing Normal University, Qujing, Yunnan Province, 655011, P. R.
China.
3Yuxi Normal University, Yuxi, Yunnan Province, 653100, P. R. China.
*Corresponding author.
E-mail:
jinglongjun666@yahoo.cn or
jinglongjunyn@126.com.
Tel:
+8613170662021.
Accepted 14 October, 2009 |
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A study was undertaken to evaluate the effects of
polysaccharide from Lycium barbarum (LBP)
in alloxan-induced diabetic mice.
The various parameters studied included body weight, fasting
blood glucose levels,
total cholesterol (TC)
and
triglyceride (TG) in diabetic and normal
mice. LBP
treatment (20, 40 mg/ kg
body weight)
for 28
days
resulted in a significant decrease in the concentration of
fasting blood glucose (FBG),
total cholesterol (TC)
and
triglyceride (TG)
in diabetes mellitus mice. Furthermore,
LBP
significantly increased
body weight (bw).
The data demonstrated
LBP
at the dose of 40 mg/kg bw exhibited the optimal effect.
Key words:
Polysaccharide from Lycium barbarum, effect,
diabetic. |
