A microbial
strain, SLO-105, isolated from Lake Oubeira sediment was
screened for its antimicrobial activity against pathogenic
bacteria and fungi. The strain showed broad-spectrum
antibacterial activity against Gram-positive bacteria
Staphylococcus aureus MRSA, Bacillus subtilus,
Micrococcus leutus, Streptococcus fecalis and
fungi Aspergillus niger and Rodotorulla
mucilaginosa. However, no activity of the strain was
observed against Gram negative bacteria Escherichia coli
and Pseudomonas aeruginosa as well as on fungi
Candida albicans. Analysis of 16S rDNA sequence and the
morphological and physiological characteristics of the
strain suggested that the isolate belonged to
Streptomyces genus.