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Phytochemical screening
and antibacterial properties of leaves of
Pongamia
pinnata
Linn. (Fabaceae) from India
S. R. Arote1,
S. B. Dahikar1* and P. G. Yeole2
1Department
of Pharmaceutical Microbiology, Sanjivani College of
Pharmaceutical Education and Research, Kopargaon-423603,
India.
2Institute
of Pharmaceutical Education and Research Borgaon (Meghe)
Wardha- 442001, India.
*Corresponding author. E-mail:
sbdahikar10@gmail.com.
Accepted
3 July, 2008 |
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Herbal
medicine is the most ancient form of health care known to
man and its being used increasingly reveals it as dietary
supplement to fight or prevent common diseases. Petroleum
ether extract, chloroform extract, ethyl acetate extract and
methanol extracts of leaves of
Pongamia pinnata
Linn.
were
prepared and antibacterial activity were studied by disc
diffusion method against certain enteric bacterial pathogens
such as Escherichia coli, Staphylococcus aureus,
Klebsiella pneumonia, Bacillus subtilis, Enterobacter
aerogenes, Pseudomonas aeruginosa, Salmonella typhimurium,
Salmonella typhi, Staphylococcus epidermidis and
Proteus vulgaris.. The methanol extracts had wide range
of antibacterial activity on these bacterial pathogens than
the petroleum ether extract. Ethyl acetate extract was
slightly higher antibacterial activity against bacterial
pathogens than chloroform extract. Phytochemical screening
of the plant leaves reveals the presence of carbohydrates,
alkaloids, flavonoids glycosides, steroids, tannins and
saponins. Antibacterial activity of various extract of
leaves of P. pinnata was carried in attempt to
support the use by medicinal practitioner for the treatment
of enteric infection.
Key
words:
Antibacterial activity,
Pongamia pinnata,
enteric bacterial pathogens. |
