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Antibacterial activity of
seed extracts of Argemone mexicana L. on some
pathogenic bacterial strains
Santosh Kumar Singh1*, Vidya Dhar Pandey2,
Aradhana Singh1 and Chandan Singh1
1Centre
of Experimental Medicine and Surgery (CEMS), Institute of
Medical Sciences (IMS), Banaras Hindu University, Varanasi -
221005, India.
2Department
of Botany, Government Post-Graduate College,
Rishikesh-249201, Uttarakhand, India.
*Corresponding author. E-mail:
singhsk71@yahoo.com.
Tel.:
+91-5426702198 (O). Mobile +91-9415389046.
Accepted 12 August, 2009 |
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Antibacterial activity of
seed extracts of Argemone mexicana L. (Papaveraceae)
was evaluated against some pathogenic bacterial strains.
Chloroform extract of seeds exhibited varying level of
antibacterial activity, with minimum inhibitory
concentrations (MIC) of 2.0 - 5.0 mg/ml, against both
Gram-positive and Gram-negative bacteria. The chloroform
extract was found to be more active than the other extracts
against all the test bacteria. MIC values were 2.0 and 3.0
mg/ml, respectively, for Staphylococcus aureus and
Pseudomonas aeruginosa and their respective
drug-resistant strains. The sensitivity of the test bacteria
varied with the species and strains. The study provides
basis for the isolation and purification of antibacterial
compound(s) from the seeds of A. mexicana L.
Key words:
Argemone mexicana,
antibacterial activity, disk diffusion method, drug
resistant. |
