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In vitro
assessment of antibacterial activity of bark extracts of
Khaya senegalensis
Sale, M.1*, De,
N. 1, Doughari, J. H.1 and
Pukuma, M. S.2
1Microbiology
Department, Federal University of Technology, Yola, P.M.B.
2076 Jimeta- Yola, Adamawa State, Nigeria.
2Biological
Sciences Department, Federal University of Technology, Yola,
P.M.B. 2076 Jimeta- Yola, Adamawa State, Nigeria.
*Corresponding author. E-mail:
musatab2002@yahoo.com.
Phone: +2348026807423.
Accepted
29 December, 2006 |
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In vitro
antibacterial activity of aqueous, ethanol and acetone
extracts of Khaya senegalensis were tested against
Staphylococcus aureus, Streptococcus pyogenes, Salmonella
typhi, Shigella dysenteriae, Klebsiella pneumoniae and
Pseudomonas aeruginosa isolated from clinical specimen.
The acetone extracts showed higher antibacterial activity
compared to the aqueous and ethanol extracts. The minimum
inhibitory concentration of acetone extracts was in the
range of 6.5 to 12.5 mg/ml while the minimum bactericidal
concentration ranges between 6.5 to 25.0 mg/ml. The
antibacterial activity of the extracts was not significantly
affected by heating at 100o C for 1 h but the
activity was lost at pH 8.0.
Key
words:
In vitro, antibacterial activity, Khaya
senegalensis. |
