The diversity of
leptin gene in Iranian native, Holstein and Brown Swiss
Mohammad Reza Nassiry1*,
Alireza Heravi Mousavi1,
1Department of Animal Science, Ferdowsi University, Mashhad, Iran.
16 February, 2008
describes genetic variability in the leptin in
Iranian native, Brown Swiss and Holstein cattle (Bos
Indicus and Bos Taurus). This is the first study of
genetic polymorphism of the leptin gene in Iranian
examined exon 2 of the leptin gene from 587 individuals in
six different populations of Iranian native cattles (86
Sarabi, 66 Taleshi, 94 Sistani, 76 Golpayegani, 104 Brown
Swiss and 161 Holstein cattle) using PCR-RFLP method.
Analysis of the frequencies of the various alleles in each
breed indicated that allele C in Sarabi, Taleshi,
Sistani, Golpayegani, Brown Swiss and Holstein cattle with
68, 55, 69, 71, 55 and 57% value were the most frequent
highest in Golpayegani (57.89%).
These new data suggest that allele frequencies of leptin
differ between the various Iranian cattle breeds.
Leptin, PCR-RFLP, Iranian native cattle.