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In vitro
antifungal activity of methanol extracts of some Indian
medicinal plants against pathogenic yeast and moulds
Jigna Parekh and Sumitra Chanda*
Phytochemical, Pharmacological and Microbiological
Laboratory, Department of Biosciences, Saurashtra
University, Rajkot 360 005, Gujarat, India.
*Corresponding author. E-mail:
sumitrachanda@yahoo.com.
Accepted
17 December, 2007 |
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The methanol extract of 9 Indian medicinal plants belonging
to 9 different families were evaluated for in vitro
antifungal activity against some yeasts including Candida
albicans (1) ATCC2091, C. albicans (2)
ATCC18804, Candida glabrata NCIM3448, Candida
tropicalis ATCC4563, Cryptococcus luteolus
ATCC32044, Cryptococcus neoformans ATCC34664,
Trichosporon beigelli NCIM3404, and some moulds such as
Aspergillus candidus NCIM883, Aspergillus flavus
NCIM538, Aspergillus niger ATCC6275 and Mucor
heimalis NCIM873. The in vitro antifungal
activity was evaluated at three different concentrations by
agar disc diffusion method and the activity obtained was not
concentration dependent.
A. flavus was the most susceptible fungal strain while
C. glabrata was the most resistant one. Saussurea
lappa showed the best antifungal activity. The results
were compared with the standard antifungals.
Key
words:
medicinal plants, antifungal activity, methanol extracts,
yeast, mould, Saussurea lappa.
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