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The anti-tick properties
of the root extracts of Senna italica subsp.
arachoides
Magano S. R.1*,
Thembo K. M.2, Ndlovu S. M.3 and
Makhubela N. F. H.3
1Department
of Biology, University of Limpopo, South Africa.
2Medical
Research Council, Cape Town, South Africa.
3Department
of Chemistry, University of Limpopo, South Africa.
*Corresponding author.
E-mail:smagano@medunsa.ac.za. Tel: (012) 521-4675, (012)
521-4246.
Accepted
15 November, 2007 |
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This study examined the anti-tick properties of the root
extracts of Senna italica subsp. arachoides
against adults of Hyalomma marginatum rufipes. Of the
hexane, chloroform, dichloromethane, ethyl acetate and
methanol extracts tested, only ethyl acetate extracts proved
to be potent against adults of H. marginatum
rufipes. The acaricidal activity of the ethyl acetate
root extract of S. italica subsp. arachoides
increased significantly (P < 0.05) with concentration when
tested against H. marginatum rufipes. The
potency of the extract persisted to the second day. The LC50
of the ethyl acetate root extract of S. italica subsp.
arachoides in 24 h was 8.66% (w/v) while in 48 h was
3.59% (w/v). Chemical characterization of the extracts
revealed 1,2-benzenedicarboxylic acid, dibutyl ester,
1,8-dihydroxy-3-methylanthraquinone, 1,2-benzenedicarboxylic
acid, bis(2-ethylhexyl) ester, hexadecanoic acid,
9-hexadecanoic acid as components.
Key
words:
Senna italica subsp. arachoides, Hyalomma
marginatum rufipes, contact toxicity, root
extract. |
