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Antioxidant activity in
some selected Indian medicinal plants
P. Suresh Kumar1
*, S. Sucheta1, V. Sudarshana
Deepa1, P. Selvamani2 and S. Latha2
1Department
of Biotechnology, Anna University, Tiruchirappalli- 620 024,
India.
2Department
of Pharmaceutical Technology, Anna University,
Tiruchirappalli- 620 024, India.
*Corresponding author E-mail:
sureshbiotech2003@yahoo.co.in.
Accepted 11
April, 2008 |
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The study was carried out to determine the antioxidant
activity of selected medicinal plants namely Albizia
amara, Achyranthes aspera, Cassia fistula, Cassia auriculata
and Datura stramonium by inhibition of lipid
peroxidation technique. The highest inhibition of lipid
peroxidation activity was observed in A. amara (96%)
followed by C. fistula (89%) and
C.auriculata (89%). The potency of protective effect of
A. amara was about 4 times greater than the synthetic
antioxidant butylated hydroxy toluene (BHT). The total
alkaloid content varied from 24.6
±
0.18 to 72.6
±
2 mg g-1 in the extracts. Flavanoid contents were
between 23.15
±
0.2 and 63.3
± 0.6 mg g-1 in the methanolic extracts of these
plants. Our study indicates that the antioxidant activity of
A. amara could be harnessed as a drug formulation.
Key
words:
Antioxidant, lipid peroxidation, alkaloids, flavonoids,
butylatedhydroxy toluene. |
