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Antibacterial activity of
Ficus capensis
Oyeleke, S. B.1*, Dauda, B. E. N.2
and Boye, O. A.1
1Department
of Microbiology, Federal University of Technology, Minna,
Nigeria.
2Department
of Chemistry, Federal University of Technology, Minna.
Nigeria.
*Corresponding author. E-mail:
droyeleke@yahoo.com.
Accepted 13 March, 2008 |
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The leaves and stem bark
of Ficus capensis were investigated for antibacterial
activity against some selected organisms at a concentration
of 2000 µg/ml using agar diffusion method. The crude leaf
extract inhibited the growth of Escherichia coli and
Shigella sp. but no activity against Salmonella
typhi. The stem bark extracts also had activity against
E. coli and Shigella sp. but no activity
against S. typhi. The phytochemical screening of the
extracts reveals the presence of alkaloids, balsams,
taninins, carbohydrates, resins, flavonoids, Sterols and
terpenes. Glycosides were absent in the leaf extract while
the stem bark extract had glycosides. Both extracts did not
posses free arthraquinones and saponins. The Minimum
inhibitory concentration (MIC) of the extracts range from
500-2000 µg/ml. The fractions obtained from the thin layer
chromatography had no activity on the test organisms. The
results from the activity of the crude extracts suggest that
F. capensis could be used in treatment of diseases
caused by these bacteria except S. typhi.
Key words:
Ficus capensis,
antibacterial, phytochemical. |
