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Preliminary study into the
long term effects of a hypoglycaemic polyherbal formula (Yem-Kem)
on some biochemical parameters in normal rabbits
Ojekale, A.
B.1*, Kappo, M.
A.1,
Agbasoro, S.2 and
Kazeem, A.2
1Department
of Biotechnology, University of the Western Cape, Bellville,
Cape Town,
South Africa.
2Department
of Biochemistry, Lagos State University, Ojo, P.M.B.001,
Apapa, Lagos,
Nigeria.
*Corresponding author.
E-mail:
aojekale@uwc.ac.za.
Accepted 29 October, 2007 |
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The blood glucose lowering
capacity of the polyherbal formula (Yem-Kem) was
investigated in this study in an in vivo clinical
trial using normal Sprague-Dawley rabbits orally
administered with the formula over a 60 day period. The
results showed that continuous exposure to the extract
resulted in an overall lowered blood glucose level, lowered
body weight and serum triglycerides, an increased alkaline
phosphatase level, and fairly stable bilirubin levels. The
formula is efficient as a hypoglycemic formulation, but its
toxicity or otherwise cannot be established by this study.
Key words:
Hypoglycaemia, serum analytes, enzymes, herbal formula,
Yem-Kem. |
