African Journal of Biotechnology
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African Journal of Biotechnology Vol. 5 (11), pp. 1142-1145, 2 June 2006 DOI: 10.5897/AJB06.168 ISSN 1684–5315 © 2006 Academic Journals
Antioxidant activity,
phenol and flavonoid contents of some selected Iranian medicinal plants
F. Pourmorad1*, S. J.
Hosseinimehr1, N. Shahabimajd2
1Department
of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of
Medical Sciences, Sari, Iran.
2Department
of Physiology and Pharmacology, Faculty of Medicine, Mazandaran University
of Medical Sciences, Sari, Iran.
*Corresponding author. E-mail:
pourmoradf@yahoo.com; Tel: 0098
911 152 2396 (mobile). Fax: 0098 152 3343082.
Accepted 10 April, 2006 |
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| Abstract | |||||
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In present study, we carried out a systematic record of the relative antioxidant activity in selected Iranian medicinal plant species' extracts. The total phenol varied from 24.1 ± 1 to 289.5 ± 5 mg g -1 in the extracts. Flavonoid contents were between 25.15 ± 0.8 and 78.3 ± 4.5 mg g-1. 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging effect of the extracts was determined spectrophotometrically. The highest radical scavenging effect was observed in Mellilotus officinalis with IC50 = 0.018 mg ml –1. The potency of radical scavenging effect of M. officinalis extract was about 4 times greater than synthetic antioxidant butylated hydroxy toluene (BHT). The greater amount of phenolic compounds leads to more potent radical scavenging effect as shown by M. officinalis extract.
Key words: Antioxidant, radical scavenger, flavonoids, phenols, 1,1-diphenyl-2-picryl hydrazyl. |
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