African Journal of Biotechnology

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Afr. J. Biotechnol.


Vol. 5 No. 1



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Rouabhi R

Djebar MR


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African Journal of Biotechnology Vol. 5 (1), pp. 045-048, 2 January 2006   

ISSN 1684–5315 © 2006 Academic Journals        

 

Full Length Research Paper

 

Toxicity evaluation of flucycloxuron and diflubenzuron on the cellular model, Paramecium sp.

 

ROUABHI, R.1*, BERREBBAH, H.2, and DJEBAR, M.R.2

 

1Department of Biology, University center Larbi Tebessi, Tebessa, 12000, Algeria.

2Laboratory of Cell toxicology, Department of Biology, Faculty of the Sciences, Annaba university, 23000, Annaba, Algeria.

 

*Corresponding author. E-mail: r_rouabhi@yahoo.fr.

 

Accepted 11 November, 2005

 

 

 
    Abstract

 

 

 

The effect of two pesticides, the diflubenzuron (DFB) and flucycloxuron (FCX) was studied on the ciliated protiste cellular model, Paramecium sp. Treatment with the DFB at 10 and 20 µg/ml reduces the growth of this protiste appreciably. The survey of the respiratory metabolism by the polarography technique (oxygen electrode) shows a sensitive inhibition of the oxygen consumption. In the case of the FCX, treatment with the two concentrations (10 and 20 µg/ml) reveals an inhibition of the ciliated protiste growth. This pesticide also inhibits the respiratory metabolism of ciliated protiste. This effect is a lot more marked with the FCX that with the DFB.

 

Key words: Paramecium sp., flucycloxuron, diflubenzuron, pesticide, respiratory metabolism.

 

 

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