African Journal of Biotechnology Vol. 5 (3), pp. 295-297, 2 February 2006   

ISSN 1684–5315 © 2006 Academic Journals        

Short Communication

Production potentials of anti-Plesiomonas shigelloides antibody

Oviasogie, F.E. and Ekhaise, F.O.*

Department of Microbiology Faulty of Science, University of Benin, P.M.B 1154, Benin City, Nigeria.

*Corresponding author. E-mail: fredfldyn@yahoo.com.

Accepted 29 September, 2005

Out of the one hundred and fifty stool human samples screened for the prevalence of Plesiomonas shigelloides, only 3 (2%) were positive for the organisms. The positive isolates were used to produce P. shigelloides antibody in experimental animals (rabbits). Autopsy revealed marked inflammation of the liver, spleen and the kidney in the experimental animals not protected with the antibodies. This study showed that the trial rabbits were suitable for the production of antibodies against P. shigelloides, and further demonstrated the diagnostic and protective potentials of the antibodies.

Key words: Plesiomonas shigelloides, experimental animals, colloidal carbon particles, antibody and antisera.