African Journal of Biotechnology Vol. 5 (10), pp. 958-959, 16 May 2006   

ISSN 1684–5315 © 2006 Academic Journals        

Short Communication

Antibacterial assessment of whole stem bark of Vitex doniana against some enterobactriaceae

KILANI A. M

Department of Botany and Microbiology, Faculty of Science University of Lagos, Akoka, Nigeria. E-mail: adetunjikilani2005@yahoo.com.

Accepted 7 March, 2006

The effects of methanolic extracts of the stem bark of Vitex doniana against some Entrobacteriaceae was investigated. Clinical isolates of Salmonella typhi, Shigella dysentariae and Escherichia coli were treated with extracts of the stem bark of V. doniana for antimicrobial activity using in vitro agar diffusion method and the minimum inhibitory concentration. The stem bark extracts were able to inhibit the growth pattern of the tested microorganisms. In all cases Shigella dysentariae showed the highest sensitivity. The results suggest that V. doniana may be valuable in the management of dysentery and gastroenteritis infections.

Key words: Vitex doniana, antimicrobial susceptibility, traditional medicine.